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Bupropion Information

What can Bupropion be used for?

Bupropion is an atypical antidepressant. It differs from the most common antidepressants such as SSRI antidepressants as it mostly affects the norepinephrine and dopamine reuptake. It inhibits the reuptake of these chemicals and thus corrects certain imbalances in the brain that might lead to the major depressive disorder. Besides this use, there are brands of Bupropion that are also used as an aid in cessation of smoking. Namely, Bupropion also has certain effects on the nicotine acetylcholine receptors and thus helps reduce the cravings for cigarettes. There are two main advantages of Bupropion over the more common antidepressants. Namely, it does not cause sexual dysfunction and weight gain which are characteristic side effects of antidepressants. In fact, there have been studies that Bupropion may even bring benefits in patients with sexual dysfunction and that it can even help in losing weight. Besides the two already mentioned uses for Bupropion, there are even more, such as in treating anxiety which is comorbid with depressive state and in the treatment of social phobia. However, there have been no benefits of Bupropion shown in cases of panic disorder. Use of Bupropion in cases of ADHD has also been studied but it is still not prescribed for this condition.

Discussing Bupropion with your healthcare provider

Discussing Bupropion with your healthcare provider is one of the most important steps in a successful and risk-free Bupropion treatment. By doing this, you avoid any unwanted side effects of Bupropion and you maximize its efficiency. It is of vital importance that you inform your doctor in case you have taken any MAO inhibitors in the last two weeks. This is important because an interaction between these two may cause life-threatening effects and it takes 14 days for the last traces of MAO inhibitors to clear out from your body. Few other conditions that will prevent you from taking Bupropion are seizure disorders, eating disorders as well as any sedative treatments or significant use of alcohol. If you have any heart disease, history of heart attack, tumors of the brain or spinal cord, seizures or head injury, if you have any liver disease, kidney disease or bipolar disorder, you will need to take extra precautions while taking v and your doctor will need to carefully titrate your dosage.

Can pregnant women take Bupropion?

It is highly inadvisable for pregnant women to take Bupropion as there is a certain risk that it might affect the health of the fetus in an adverse way. This is also true for breastfeeding as Bupropion may pass into milk. If you wish to start breastfeeding or if you become pregnant and you are already using Bupropion, make sure you inform your doctor about this.

How is Bupropion properly taken?

Bupropion is a powerful prescription drug and it should therefore be taken in strict accordance with the prescription. Any changes to the regimen that you make on your own can only bring detrimental effects to your health and your condition. It is possible that your physician will change your dosage in order to establish the one that will work best for you. If you are using Bupropion in order to stop smoking, you will need to give up cigarettes in the second week of your treatment. You will also need to talk to your doctor about use of any nicotine patches or similar aids as you might experience nicotine overdose when using them along with Bupropion. If you are using Bupropion for your depression, you will need to make sure you notice and report any significant mood changes in the first few weeks. This is important as all antidepressants may cause certain suicidal thoughts in patients. If you are drinking significant amounts of alcohol or if you used to and have stopped prior to your Bupropion treatment, your doctor needs to be aware of this, as this increases the risk of you experiencing convulsions.

Possible Bupropion side effects

You should not experience any serious side effects of Bupropion in case you are taking it as prescribed, but there is always possibility that you might and you need to talk to your doctor in case these occur: convulsions, hallucinations, unusual behavior or thoughts, troubles concentrating, confusion, severe skin rash, feeling ill in general, hyperactivity, suicidal thoughts, restlessness, irritability, aggressiveness, hostility, agitation, impulsiveness, panic attacks, anxiety. Less serious side effects are also rare but more common, including headaches, dry mouth, insomnia, constipation, nausea, vomiting, weight changes, changes in your sex drive, increased sweating, appetite changes, dizziness, mild itching, and tremors.

A list of possible Bupropion interactions

Keep in mind that this is an incomplete list: other antidepressants, asthma medications, antihistamines, birth control pills, certain antibiotics, urinary tract medications, diet pills, malaria medications, Parkinson's disease drugs, immunosuppressants, diabetes medications, ADHD medications, motion sickness medications, narcotics, irritable bowel syndrome drugs, theophylline, steroids, sedatives, cancer medications, hypertension and heart medications, anticoagulants and HIV medications.

Bupropion overdose - what to do?

In case of a Bupropion overdose it is crucial to seek emergency medical assistance as soon as possible, as it can be lethal. Symptoms of a Bupropion overdose include hallucinations, shallow breathing, muscle stiffness, uneven heartbeat and fainting.

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