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Sibutramine Information
What kind of a drug is Sibutramine?
Sibutramine is a stimulant drug which is used in weight-loss regimens as a dietary aid. While it is related to certain extent to amphetamines, it has a mechanism of action that is completely different to the one that amphetamines have. Namely, amphetamines usually work by promoting the release of certain chemicals like norepinephrine and serotonin, while Sibutramine inhibits the reuptake of these chemicals, resulting in Sibutramine being categorized as a serotonin-norepinephrine reuptake inhibitor, or SNRI for short. SNRIs are usually used in treating depressive disorders, but Sibutramine has no effect in elevating mood. It is therefore used only as a hunger-suppressant, due to the fact that the elevated levels of these chemicals cause the feeling of satiation. Due to the fact that it is a very powerful drug, it is mainly prescribed for use in patients who are at an increased risk due to suffering from high blood pressure or diabetes for example.
Talk to your doctor about using Sibutramine
It is very important that you discuss the use of Sibutramine with your healthcare provider, due to the fact that it may cause certain adverse effects to the cardiovascular system, mainly in people who are already having issues with the same. Your doctor will need to know if you have any conditions that might be prevent you from using Sibutramine due to the fact that it may cause exacerbation of these conditions, including allergy to this medication, eating disorders like bulimia and anorexia, increased pulmonary blood pressure, uncontrolled high blood pressure, severe high blood pressure, severe diseases of liver or kidneys, or if you have a history of the following cardiovascular problems: strokes and mini-strokes, arteriosclerosis, heart failure, heart attacks, irregular heartbeat, chest pain. You will also not be able to take Sibutramine if you are taking MAO inhibitors, SSRIs or other weight-loss medications. In some other cases, you might be still able to take Sibutramine, but you will need to take extra precaution while taking it, like seizure disorders, underactive thyroid, gallbladder problems, narrow-angle glaucoma, pheochromocytoma, arrhythmias, bleeding problems, high blood pressure and other heart problems.
Pregnancy and Sibutramine
Sibutramine is classified as FDA pregnancy category C, which means that there are risks of this medication having adverse effects to the health of the fetus and the nursing child. This is the reason why you should let your doctor know if you are breastfeeding or pregnant before they prescribe you with this medication. You will also need to tell them as soon as you find out that you have become pregnant if this happens during your Sibutramine treatment. In such a case, your doctor will weigh the potential risks with the benefits of Sibutramine. However, it is more probable that you will need to stop taking this drug.
What to keep in mind when taking Sibutramine?
Sibutramine works best if it is taken according to your prescription. This way, you also avoid experiencing any side effects of this medication. It is very dangerous to exceed the recommended dose and to continue taking Sibutramine after the regimen is completed. An overdose on Sibutramine is particularly dangerous as it may be lethal in extreme cases. The most important thing to keep in mind when Sibutramine is in question is that the effects of this medication will only be felt by patients who remember to eat properly and to exercise regularly. It is only a part of the more extensive weight-loss treatment and the effects of Sibutramine will be much less pronounced if you do not adhere to the treatment in its entirety. Sibutramine is also known to cause insomnia, which is why it is not supposed to be taken lat in the day. Your doctor might want to check your blood pressure, as well as your weight. You need to make those appointments as they are necessary for your doctor to be able to tell if your Sibutramine treatment is going as planned. If you should feel side effects like dizziness or blurred vision, you will need to wait for them to wear off before you drive or do anything potentially hazardous.
Possible side effects of Sibutramine
Sibutramine has been criticized for many side effects that it can cause, especially the more serious ones that it can cause to the cardiovascular system. However, this is nowhere near as dramatic as it has been presented and serious side effects are mostly avoided if the drug is taken as recommended. Still, there is always possibility of them occurring, as well as those less serious ones. For the list of all the possible side effects of Sibutramine, you should consult the label or your doctor, maybe the pharmacist.
Short list of most common Sibutramine interactions
Keep in mind that this is not a complete list of possible Sibutramine interactions: cyclosporine, anticoagulants, ephedrine, tryptophan, SSRIs, pentazocine, narcotics, lithium, MAOIs, dihydroergotamine, antifungals, dextromethorphan.
How to deal with a Sibutramine overdose
In case a Sibutramine overdose is suspected, make sure that you seek emergency medical assistance. The symptoms that might occur include fast heartbeat, irregular heartbeat, severe headache and dizziness.
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