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Tadalafil Information
Tadalafil Description and Uses
Tadalafil is a type of drug called a PDE5 inhibitor which is more commonly known by its brand name of Cialis. Along with other PDE5 inhibitors such as Sildenafil and Vardenafil, Tadalafil is used for treating erectile dysfunction and a rare type of high blood pressure in the lungs. In 2003, Tadalafil became the third drug of its kind to be FDA approved. While still not surpassing the popularity of Sildenafil (Viagra) for treating erectile dysfunction, Tadalafil has gotten significant attention because of its longer lasting effects.
Tadalafil Compared to other PDE5 Inhibitors
Tadalafil is very similar to the other drugs in its class, Sildenafil (Viagra) and Vardenafil (Levitra). They are all PDE5 inhibitors and share the same indications, possible side effects, and other properties. However, on a molecular level, these drugs for erectile dysfunction work in different ways. Because of this, it is possible that one PDE5 inhibitor may not be effective in a patient whereas another will be. It is common for doctors to prescribe Tadalafil to patients that did not positively respond to either Sildenafil or Vardenafil. The main difference between Tadalafil and the other PDE5 inhibitors though is its half-life. Tadalafil has a half-life of about 17 ½ hours which means that its effects can be felt for up to 36 hours.
How Does Tadalafil Work?
Tadalafil is a type of drug called a phoshodiesterase type 5 inhibitor or PDE5 inhibitor for short. When sexual stimulation occurs in a male, a series of complex chemical reactions occurs. One of these reactions involves the relaxation of smooth muscle tissues in the penis, thus allowing more blood to flow to the penis and increasing erection strength and duration. The body will release the chemical PDE5 in order to contract the penile muscle tissue, reduce blood flow, and terminate erection. As Tadalafil inhibits PDE5, achieved erections become higher quality and longer lasting. Because Tadalafil only prevents the discontinuation of erections, it will not cause an erection to appear without sexual stimulation.
How is Tadalafil Taken?
Tadalafil should only be taken if it has been prescribed to you by your health care provider. Not all erectile dysfunction treatments are the same and Tadalafil may not be the right choice for you. When prescribed, Tadalafil is usually only taken on an as-needed basis for erectile dysfunction about 1 hour before anticipated sexual activity. For some men, Tadalafil has shown effective in as short a time as 15 minutes after taking the medicine. Some patients may be instructed to take Tadalafil once daily for erectile dysfunction. If taking Tadalafil for high blood pressure in the lungs, then it is typically taken once per day. Unless you have been told otherwise, you may take Tadalafil with or without foods.
Tadalafil Dosage
For treating erectile dysfunction on an as-needed basis, Tadalafil is usually taken in dosage amounts of 10 mg. Dosage may be increased up to a maximum of 20 mg or decreased to 5 mg depending on how the patient responds to treatment. For daily treatment of erectile dysfunction, then Tadalafil is usually taken in lower dosages of 2.5 mg once per day. This dosage may be increased to 5 mg if needed. When taking Tadalafil for high blood pressure in the lungs, the dosage amount is generally 40 mg once per day. Elderly patients, impaired patients, or those taking certain other medications may require a different dosage. Always take Tadalafil precisely as it was prescribed to you by your health care professional.
What You Should Know before taking Tadalafil
Tadalafil is generally safe for more patients to use. However, it can put an extra strain on the cardiovascular system. When this strain is combined with other types of cardiovascular stress (such as during strenuous sexual activity), serious health consequences could result. If you become very dizzy, have chest pain, or faint during sexual activity while taking Tadalafil, immediately get medical attention.
Possible Side Effects from Tadalafil
It is common and generally unserious for Tadalafil to cause these side effects in patients: migraine, dyspepsia, backache, sore muscles, congestion, flushing, limb soreness, or slight change to eyesight. You should tell your doctor if these effects are continual or worrisome. Tadalafil is associated with a rare but serious condition called NAION in which sudden blindness occurs. Immediately get medical attention should this happen. In uncommon cases, Tadalafil has led to males having long-lasting (more than 4 hours) and/or painful erections. This could be a serious condition called priapism which may lead to permanent damage. Priapism merits immediate medical attention. Let your health care provider know if you have any unusual hearing changes while taking Tadalafil.
Tadalafil Contraindications
Tadalafil may not be safe for everyone. The following conditions are contraindicated for Tadalafil: penile problems (including deformations), history of priapism, anemia, cancer, ocular problems, ulcer, cardio problems, recent strokes, hypotension, hypertension, pregnancy, or breastfeeding. Note that your doctor may still prescribe you Tadalafil even if you have one of these conditions. However, your dosage may need adjusting or you may need to follow special instructions during treatment.
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