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Zolpidem Information
Zolpidem Description and Indications
Zolpidem is a type of hypnotic drug which is approved for treating insomnia in which the patients have difficulties falling asleep (as opposed to staying asleep once sleep has begun). The drug is only indicated for treatment on short-term bases, typically no more than 14 days. Zolpidem is commonly known by its trade name of Ambien though it is also available in many other brand names as well as generic forms.
How Does Zolpidem Work?
Though Zolpidem is not a benzodiazepine drug, it has a very similar mechanism of action to these types of drugs. It works by enhancing the neurotransmitter gamma-aminobutyric acid, better known as GABA. The main role of GABA is to call neuron activity. Since GABA is the most predominant neurotransmitter in the body with receptors located throughout the body, it can have an overall calming effect including sedation. When Zolpidem is taken, it quickly acts upon GABA and generally creates a sedating effect within 15 minutes of the dosage. This allows patients to easily fall asleep. However, the effects of Zolpidem generally wear off very quickly (about 2 or 3 hours). Because of this, Zolpidem is not effective in helping patients stay asleep, just aiding in falling asleep.
What You Need to Know before taking Zolpidem
Zolpidem use can lead to a drug tolerance, dependency, and withdrawal effects. Many patients who initiated treatment with Zolpidem for insomnia inadvertently found themselves addicted to the drug. There are many ways that a drug addiction to Zolpidem can occur but it often starts with the patient building up a tolerance. Once tolerance has occurred, Zolpidem isn't effective in its prescribed dosages and the patient may decide to increase dosage in order to get the beneficial effects. Long-term use, especially in high dosages, can cause the body to physically need Zolpidem in order to properly function. This is known as a drug dependency. A dependency on Zolpidem can become worse as tolerances get higher. It is important that you inform your doctor immediately when Zolpidem starts to lose effectiveness in you or the first sign of cravings for the drug.
Withdrawal Symptoms from Zolpidem
After stopping treatment with Zolpidem, it is common for patients to experience a condition called "rebound insomnia." The insomnia typically occurs in the first few nights after cessation of treatment but will generally go away. Let your doctor know if your insomnia persists. If the patient has built up a high tolerance and large dependency to Zolpidem, then serious and long-lasting withdrawal effects can occur with Zolpidem use is stopped. Some of these Zolpidem withdrawal symptoms may include: hallucinations, seizure, mood changes, insomnia, body pains, abdominal cramps, and perspiration. You may need to have your dosage of Zolpidem reduced slowly over time in order to avoid severe withdrawal symptoms.
Who Should Not Take Zolpidem?
Patients who are at risk of developing a drug dependency or addiction to Zolpidem should not take this medicine. This may include patients with a personal or family history of drug/substance abuse or psychiatric problems. Zolpidem may not be safe to take if you have certain health risk factors. Do not take Zolpidem without first informing your health care provider of your full medical history, especially of: allergies, kidney or hepatic impairment, mental health disorders, respiratory problems, or myasthenia gravis. It is advised against taking Zolpidem during pregnancy as it can harm an unborn child. Taking Zolpidem while breastfeeding could also harm a nursing child. Do not take Zolpidem while pregnant or breastfeeding without first consulting your health care provider.
Side Effects of Zolpidem
It is common for Zolpidem to make you feel dizzy. It may also cause you to feel tired during your normal waking hours. Let your doctor know if these side effects continue or get worse as your dosage may need adjustment. In the event that you have any of these uncommon side effects, you should contact your doctor at once: amnesia, strange moods/behaviors (such as becoming depressed, suicidal, delusional, angry, or aggressive), or performing activities while asleep (such as sleepwalking or having conversations while asleep).
Recreational Use of Zolpidem
Zolpidem has many similar qualities to benzodiazepine drugs and has the potential to be abused. In large dosages, Zolpidem may produce hallucinations, mild euphoria, or a bodily sedation. Zolpidem should never be used unless it was prescribed to you by a doctor and it should never be used in any other way than prescribed. This medicine can be habit forming and users may develop a severe drug dependency from Zolpidem abuse.
Zolpidem Overdose
Never use more Zolpidem than you were prescribed as a serious overdose could occur. The most common signs of overdose on Zolpidem are respiratory depression and a slump so deep that the patient cannot be awoken from it. If you suspect that someone has overdosed on Zolpidem, even if there are currently no symptoms of overdose, you should immediately seek out emergency medical help.
Notes about taking Zolpidem
Never take Zolpidem unless you intend on getting a minimum of 7 hours sleep after the dosage. Before taking prescription drugs for insomnia, talk to your doctor about what could be causing your insomnia. There may be safer methods of treating your insomnia such as exercising, keeping a sleeping schedule or avoiding caffeine.
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